产品名称：Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
产品CAS：
规格含量：10g
产品价格：面议
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产品详细介绍
标准品编号:
I824640
名称:
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt
别名:
N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2-((Hydroxy(phenoxy)phosphoryl)amino)propanoate Sodium Salt
参考CAS号:
free acid: 1520010-86-9
分子式:
C₁₂H₁₇NNaO₅P
分子量:
309.23
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt is an impurity of Sofosbuvir (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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