产品编号：Z157502

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	Z157502
名称:	ZD 7288-d3
别名:	N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino-d3)-N-phenyl-4-pyrimidinamine Hydrochloride; N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino-d3)-N-phenyl-4-pyrimidinamine Monohydrochloride; ICI-D 7288-d3;
参考CAS号:	133059-99-1-unlabelled
分子式:	C₁₅H₁₈D₃ClN₄
分子量:	295.83
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled ZD 7288 (Z157500). ZD 7288 is a selective Ih channel inhibitor. ZD 7288 is an sino-atrial node function modulator; blocks the hyperpolarization activated cation current If. ZD 7288 blocks Ih in central neurons. ZD 7288 increases NMDVIP(LA)evoked noradrenalin release in rat brain in vitro.
参考文献	Vera, P., et al.: Brain Res. Bull., 29, 651 (1992), Su, X., et al.: J. Neurophysiol., 77, 1566 (1997), Ishii, T., et al.: J. Biol. Chem., 274, 12835 (1999), Masuda, N., et al.: Brain Res., 1096, 40 (2006),