产品编号：W950005

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	W950005
名称:	WYE-687
别名:	Methyl 4-(4-morpholino-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d] pyrimidin-6-yl)phenylcarbamate Acid;
CAS号:	1062161-90-3
分子式:	C₂₈H₃₂N₈O₃
分子量:	528.61
类别:	Research Tools;
应用:	WYE-687 is an ATP-competitive and selective inhibitor of mammalian target of rapamycin (mTOR). Studies have shown the combination of Ras-Raf-MEK1/2 inhibitors with WYE-687 may overcome resistance to mTorKIs thus may be an effective additive therapy for treatment of patient with renal cell carcinoma or colorectal cancer.
参考文献	Huang, Shile., et al.: Cell Cycle, 11, 844 (2012); Yu, K., et al.: Cell Rsch., 15, 6232 (2009);