产品编号：W700100

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	W700100
名称:	WWL123
别名:	N-([1,1'-Biphenyl]-3-ylmethyl)-N-methyl-carbamic Acid 4'-(Aminocarbonyl)[1,1'-biphenyl]-3-yl Ester;
CAS号:	1338575-41-9
分子式:	C₂₈H₂₄N₂O₃
分子量:	436.5
类别:	Research Tools;
应用:	WWL123 is a brain penetrant inhibitor of ABHD6 that shows 10-fold selectivity for ABHD6. This inhibition has shown to decrease seizure incidence in a genetic mouse model for juvenile Huntington’s disease.
参考文献	Bachovchin, D. et al.: Proc. nat. Acad. Sci. U.S.A., 107, 20941 (2010); Naydenov, A. et al.: Neuron, 83, 361 (2014); Blankman, J. et al.: Chem. Biol. 14, 1347 (2007);