产品编号：V127965
产品规格：250mg
产品价格：面议
| 标准品编号: | V127965 |
| 名称: | Verazide |
| 别名: | [(3,4-Dimethoxyphenyl)methylene]hydrazide 4-Pyridinecarboxylic Acid; Veratrylidenehydrazide Isonicotinic Acid; 1-Isonicotinoyl-2-veratrylidenehydrazine; 3,4-Dimethoxybenzaldehyde Isonicotinoylhydrazone; NSC 180261; Nicotazide; N'-Veratrylideneisoniazid; Veratraldehyde Isonicotinoylhydrazone; Verazina; 2-[(3,4-Dimethoxyphenyl)methylene]hydrazide; 4-Pyridinecarboxylic Acid; |
| CAS号: | 93-47-0 |
| 分子式: | C₁₅H₁₅N₃O₃ |
| 分子量: | 285.3 |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Verazide is derived from Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic). |
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