产品编号：V118500
产品规格：10mg
产品价格：面议
| 标准品编号: | V118500 |
| 名称: | Vemurafenib |
| 别名: | N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX 4032; RG 7204; Ro 51-85426; |
| CAS号: | 918504-65-1 |
| 分子式: | C₂₃H₁₈ClF₂N₃O₃S |
| 外观: | 白色固体 |
| 熔点: | >263ºC (dec.) |
| 分子量: | 489.92 |
| 储存: | 冰箱 |
| 溶解度: | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Potent B-Raf inhibitor |
| 参考文献 | |
