产品编号：V097102

产品规格：2.5mg

产品价格：面议

---

产品详情

标准品编号:	V097102
名称:	Vandetanib-d4
别名:	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[[1-methyl-4-(piperidinyl-d4)]methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[[1-methyl(piperidin-4-yl)-d4]methoxy]quinazoline; ZD 6474-d4; Zactima-d4;
CAS号:	1215100-18-7
参考CAS号:	Unlabelled: 443913-73-3
分子式:	C₂₂H₂₀D₄BrFN₄O₂
分子量:	479.38
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A labelled Vandetanib; a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of vandetanib plus docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC).
参考文献	Bruns, C., et al.: Clin. Cancer Res., 6, 1936 (2000); Hennequin, L., et al.: J. Med. Chem., 45, 1300 (2002); Park, M., et al.: J. Biol. Chem., 278, 50624 (2003); Arao, T., et al.: Cancer Res., 64, 9101 (2004); Prueitt, R., et al.: Int. J. Cancer, 120, 796 (2007);