产品编号：V097100

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	V097100
名称:	Vandetanib
别名:	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; ZD 6474; Zactima;
CAS号:	443913-73-3
参考CAS号:	Hydrochloride: 443913-73-3 / TFA: 338992-53-3
分子式:	C₂₂H₂₄BrFN₄O₂
外观:	白色至淡黄色固体
熔点:	>222°C (dec.)
分子量:	475.35
储存:	-20˚C Freezer
溶解度:	DMSO (Slightly, Heated), Methanol (Slightly, Heated)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Vandetanib is a once-daily oral inhibitor of vascular endothelial growth factor receptor-2 and epidermal growth factor receptor kinase activity. The activity of Vandetanib plus Docetaxel was assessed in patients with previously treated non-small-cell lung cancer (NSCLC).
参考文献	Bruns, C., et al.: Clin. Cancer Res., 6, 1936 (2000), Hennequin, L., et al.: J. Med. Chem., 45, 1300 (2002), Park, M., et al.: J. Biol. Chem., 278, 50624 (2003), Arao, T., et al.: Cancer Res., 64, 9101 (2004), Prueitt, R., et al.: Int. J. Cancer, 120, 796 (2007),

Download MSDS File