产品编号：T773508
产品规格：1mg
产品价格：面议
| 标准品编号: | T773508 |
| 名称: | TAS-120 |
| 别名: | 1-[(3S)-3-[4-Amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one |
| CAS号: | 1448169-71-8 |
| 分子式: | C₂₂H₂₂N₆O₃ |
| 分子量: | 418.45 |
| 类别: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | TAS-120 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor TAS-120 selectively and irreversibly binds to and inhibits FGFR, which may result in the inhibition of both the FGFR-mediated signal transduction pathway and tumor cell proliferation, and increased cell death in FGFR-overexpressing tumor cells. FGFR is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival and its expression is upregulated in many tumor cell types. |
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