产品编号：T542495

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	T542495
名称:	(S)-Topotecan
别名:	(S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Hycamptamine; Hycamptin; NSC 609699; Nogitecan; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan Lactone
CAS号:	123948-87-8
分子式:	C₂₃H₂₃N₃O₅
外观:	Yellow Solid
熔点:	>150°C (dec.)
分子量:	421.45
储存:	-20°C Freezer
溶解度:	Aqueous Acid (Slightly, Heated), DMSO (Slightly)
类别:	Research Tools; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-Topotecan is a DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. Topotecan hydrochloride is a chemotherapy agent that is a topoisomerase 1 inhibitor.
参考文献	Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990); BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991); Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992)

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