产品编号：T338200
产品规格：10mg
产品价格：面议
| 标准品编号: | T338200 |
| 名称: | TH-302 |
| 别名: | N,N'-Bis(2-bromoethyl)phosphorodiamidic Acid (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl Ester; |
| CAS号: | 918633-87-1 |
| 分子式: | C₉H₁₆Br₂N₅O₄P |
| 外观: | 白色至淡黄色固体 |
| 熔点: | 97-98°C |
| 分子量: | 449.04 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell |
| 参考文献 | |
