产品编号：T294920

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	T294920
名称:	(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine Di-p-toluoyl-L-tartaric Acid Salt
别名:	(2S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine Di-p-toluoyl-L-tartaric Acid Salt; (-)-5-Methoxy-N-propyl-2-aminotetralin Di-p-toluoyl-L-tartaric Acid Salt
参考CAS号:	Free Base: 101403-24-1
分子式:	C₃₄H₃₉NO₉
外观:	Solid
分子量:	605.67
溶解度:	Methanol
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine is an intermediate in the production of antipsychotic agents and antiparkinson medications. (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine Di-p-toluoyl-L-tartaric Acid Salt is an impurity in the synthesis of ent-Rotigotine (R700705), which is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
参考文献	Homan, E., et al.: Bioorg. Med. Chem., 7, 1263 (1999); Biswas, S., et al.: J. Med. Chem., 51, 101 (2008); Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989); Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997); Ferreira, J., et al.: Lancet, 355, 1333 (2000); Arnulf, I., et al.: Neurology, 58, 1019 (2002); Wisor, J., et al.: Neuroscience, 132, 1027 (2005)