产品编号:T293862
产品规格:50mg
产品价格:面议
| 标准品编号: | T293862 |
| 名称: | 2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine |
| 别名: | S 107-d3; |
| CAS号: | 1167435-22-4 |
| 参考CAS号: | 927871-76-9-unlabelled |
| 分子式: | C₁₁H₁₂D₃NOS |
| 分子量: | 212.33 |
| 类别: | Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | t is a labelled benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance. |
| 参考文献 | |