2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine

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产品编号:T293862

产品规格:50mg

产品价格:面议


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标准品编号: T293862
名称: 2,3,4,5-Tetrahydro-7-methoxy-4-(methyl-d3)-1,4-benzothiazepine
别名: S 107-d3;
CAS号: 1167435-22-4
参考CAS号: 927871-76-9-unlabelled
分子式: C₁₁H₁₂D₃NOS
分子量: 212.33
类别: Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用: t is a labelled benzothiazepine derivative that binds the RyR1 channel and enhances the binding affinity of Calstabin-1. By preventing the depletion of Calstabin-1 from the RyR1 complex, S 107 slows muscle fatique and reduces muscle damage in exercised mice. In a murine model of Duchenne muscular dystrophy, S 107 reduces biochemical and histological evidence of the muscle damage associated with muscular dystrophy, improves muscle function, and increases exercise performance.
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