产品编号：T292625

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	T292625
名称:	Tetradecylthioacetic Acid
别名:	TTA; 1-Mono(carboxymethylthio)tetradecane;
CAS号:	2921-20-2
分子式:	C₁₆H₃₂O₂S
外观:	白色固体
熔点:	63-66°C
分子量:	288.49
储存:	-20°C Freezer
溶解度:	Dichloromethane (Slightly), DMSO (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Lipids/Fatty Acids, Glycerol Derivatives;
应用:	TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proliferation. TTA completely prevents high fat diet-induced insulin resistance and adiposity in Wistar rats. Activates rodent PPAR’s with rank order PPARα>PPARδ>PPARγ.
参考文献	Madsen, L., et al.: J. Lipid Res., 43, 742 (2002), Kronstad, K.J., et al.: Chem. Biol., 10, 609 (2003, Berge, K., et al.: J. Lipid Res., 44, 118 (2003),