产品编号：S255613

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S255613
名称:	Sematilide Hydrochloride
别名:	CK 1752A; Sematilide monohydrochloride monohydrate; N-(2-Diethylaminoethyl)-4-(methanesulfonamido)benzamide hydrochloride
CAS号:	101526-62-9
参考CAS号:	101526-83-4
分子式:	C₁₄H₂₃N₃O₃S • (HCl)
分子量:	313.423646
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.
参考文献	Tsuchida Ami., et al.: J. Cogn. Neurosci., 21,Â2263 (2009); Chen, Chih Ming., et al.: Drug Development and Industrial PharmacyÂ(1990),Â16(3),Â379-94.