产品编号：R143330
产品规格：1mg
产品价格：面议
| 标准品编号: | R143330 |
| 名称: | Regorafenib N-β-D-Glucuronide O-Tetraacetate |
| 别名: | (2R,3R,4S,5S,6S)-2-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate |
| 分子式: | C₃₄H₃₁ClF₄N₄O₁₂ |
| 外观: | Light Brown Solid |
| 分子量: | 799.08 |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides; |
| 应用: | Regorafenib N-β-D-Glucuronide O-Tetraacetate is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt (R143320), which is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. |
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