PSI-7977-d6

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产品编号:P839644

产品规格:2.5mg

产品价格:面议


产品详情

标准品编号: P839644
名称: PSI-7977-d6
别名: N-​[[P(S)​,​2'R]​-​2'-​Deoxy-​2'-​fluoro-​2'-​methyl-​P-​phenyl-​5'-​uridylyl]​-​L-alanine 1-​(Methyl-​d3)​ethyl-​2,​2,​2-​d3 Ester
CAS号: 1868135-06-1
参考CAS号: 1190307-88-0
分子式: C₂₂H₂₃D₆FN₃O₉P
分子量: 535.49
类别: Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
应用: Isotope labelled PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
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