产品编号：P840805
产品规格：100mg
产品价格：面议
| 标准品编号: | P840805 |
| 名称: | 2-Pyrazinecarbonyl Chloride |
| 别名: | Pyrazine-2-carboxylic Acid Chloride; Pyrazinoic Acid Chloride; Pyrazinoyl Chloride; Pyrazinecarbonyl Chloride; |
| CAS号: | 19847-10-0 |
| 分子式: | C₅H₃ClN₂O |
| 分子量: | 142.54 |
| 类别: | Building Blocks; Miscellaneous; |
| 应用: | 2-Pyrazinecarbonyl Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. |
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