产品编号：P458545

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	P458545
名称:	(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-aminopentyl-1-boronate
别名:	N-((S)-1-Oxo-3-phenyl-1-(((R)-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)pentyl)amino)propan-2-yl)pyrazine-2-carboxamide
分子式:	C₂₉H₃₉BN₄O₄
外观:	Foam
分子量:	518.46
溶解度:	DCM
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-aminopentyl-1-boronate is an intermediate in the preparation of Bortezomib (B675700), a dipeptidyl boronate proteasome inhibitor.
参考文献	Zhu, Y., et al.: Bioorg. Med. Chem., 14, 1483 (2006), Dorsey, B., et al.: J. Med. Chem., 51, 1068 (2008), Zhu, Y., et al.: Eur. J .Med. Chem., 44, 1486 (2009),