产品编号：P294492

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	P294492
名称:	PHVIP(LA)848125-d3
别名:	Milciclib-d3; N,1,4,4-tetramethyl-8-((4-(4-methylpiperazin-1-yl)phenyl)amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide-d3
参考CAS号:	802539-81-7 unlabelled
分子式:	C₂₅H₂₉D₃N₈O
分子量:	463.59
类别:	Research Tools;
应用:	PHVIP(LA)848125-d3 is labelled PHVIP(LA)848125 (P294490) which is a cyclin dependent kinase (CDK) inhibitor. Oral PHVIP(LA)848125 showed antitumor activity via dual targeting of cyclin-dependent kinase and tropomyosin receptor kinase families in human carcinoma cell and xenografted mouse model of carcinoma.
参考文献	Brasca, M.G., et. al.: J. Med. Chem., 52, 5152 (2009); Albanese, C., e. al.: Mol. Cancer Ther., 9, 2243 (2010)