产品编号：P294095

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	P294095
名称:	PFK 15
别名:	1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one;
CAS号:	4382-63-2
分子式:	C₁₇H₁₂N₂O
外观:	Light Beige to Beige Solid
熔点:	>156°C (dec.)
分子量:	260.29
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	PFK 15 is a novel inhibitor of glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3). It suppresses the glucose uptake and growth of Lewis lung carcinomas in syngeneic mice, and induces apoptosis in abnormal cells.
参考文献	Clem, B., et al.: Mol. Cancer Ther., 12, 1461 (2013); Brooke, D., et al.: Bioorg. Med. Chem., 22, 1029 (2014);