产品编号：P217480

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	P217480
名称:	PD-149163
别名:	N2-[(2S)-2,6-Diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-L-leucine Ethyl Ester; PF-01472472; (S)-N-[N-[N-[1-[N2-(2,6-Diaminohexyl)-L-lysyl]-L-prolyl]-L-tryptophyl]-3-methyl-L-valyl]-L-leucine Ethyl Ester;
CAS号:	169528-11-4
分子式:	C₄₂H₇₁N₉O₆
分子量:	798.07
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	PD 149163 is a selective, brain penetrating Neurotensin NTR1 receptor agonist. Neurotensin agonists such as PD 149163 block the prepulse inhibition deficits produced by a 5-HT2A and an α1 agonist. As a result, PD 149163 shows pro-cognitive, antipsychotic and anxiolytic effects.
参考文献	Feifel, D. et al.: Neuropsychophamacology, 28, 651 (2003); Shilling, P.D. et al.: Psychopharmacolgy, 175, 353 (2004);