产品编号：P217475
产品规格：100mg
产品价格：面议
| 标准品编号: | P217475 |
| 名称: | PD-123319 Bis(Trifluoroacetic Acid Salt) Hydrate |
| 别名: | (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319 Bis(trifluoroacetate) Salt Hydrate; |
| 参考CAS号: | Freeacid: 130663-39-7; Anhydrous salt: 136676-91-0 |
| 分子式: | C₃₁H₃₂N₄O₃•2C₂HF₃O₂•xH₂O |
| 外观: | Pale Beige to 淡黄色固体 |
| 熔点: | 111-114°C |
| 分子量: | 736.66 |
| 储存: | 冰箱 |
| 溶解度: | Chloroform (Slightly), Methanol (Slightly) |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | A selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells |
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