产品编号：P141015

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	P141015
名称:	Paliperidone Laurate
别名:	3-(2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-9-yl Dodecanoate;
分子式:	C₃₅H₄₉FN₄O₄
外观:	白色至淡黄色固体
熔点:	>105°C (dec.)
分子量:	608.79
储存:	-20°C Freezer, Under inert atmosphere
溶解度:	Chloroform (Slightly), Dichloromethane (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Paliperidone Laurate is related to Paliperidone (P141000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Also related to Paliperidone Palmitate (P141020) that is long-acting injectable atypical antipsychotic, used in the treatment of schizophrenia.
参考文献	Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996); Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998); Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001); Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005); Hough, D. et al.: Prog. Neuro-psychophamacol. Biol. Psych., 33, 1022 (2009); Samtani, M.N. et al.: Clin. Pharmacokin., 48, 585 (2009); Nasrallah, H.A. et al.: Neuropsychopharmacology, 35, 2072 (2010);