产品编号：O878750

产品规格：0.5mg

产品价格：面议

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产品详情

标准品编号:	O878750
名称:	3,3'-Oxy-venetoclax
分子式:	C₄₅H₄₈ClN₇O₈S
分子量:	882.42
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3,3'-Oxy-venetoclax is a human major metabolite of ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.
参考文献	Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);

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