产品编号：N926630

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	N926630
名称:	5-Nitro-2-(propylthio)pyrimidin-4-ol
分子式:	C₇H₉N₃O₃S
分子量:	215.23
类别:	Building Blocks; Miscellaneous;
应用:	5-Nitro-2-(propylthio)pyrimidin-4-ol is an intermediate used in the synthesis of 4-Chloro-5-nitro-2-(propylthio)pyrimidine (C374095), which is an impurity of the drug Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).
参考文献	Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)