产品编号：N888600
产品规格：10mg
产品价格：面议
| 标准品编号: | N888600 |
| 名称: | N-(4-piperazinyl)-oxide ABT 199 |
| 别名: | 4-(3-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 1-Oxide; Venetoclax Metabolite M6 |
| 分子式: | C₄₅H₅₀ClN₇O₈S |
| 外观: | Yellow to Dark Yellow Solid |
| 熔点: | >170°C (dec.) |
| 分子量: | 884.44 |
| 储存: | -20°C Freezer |
| 溶解度: | DMSO (Slightly) |
| 类别: | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | N-(4-piperazinyl)-oxide ABT 199 can be obtained from ABT 199 (A112430) which is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
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