产品编号：N385745

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	N385745
名称:	(+)-Nefopam
别名:	1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, (S)-; (1S)-3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine; S-Nefopam
CAS号:	110011-82-0
分子式:	C₁₇H₁₉NO
分子量:	253.34
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(+)-Nefopam inhibits the uptake of 5-hydroxytryptamine (5-HT), noradrenaline and dopamine in synaptosomal preparations from rat forebrain, hippocampus and striatum. A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.
参考文献	Rosland, J. H., et al.: J. Pharm. Pharmacol, 42, 437 (1990); Bassett, et al.: Br. J. Pharmacol., 37, 69 (1969), Klohs, et al.: Arzneim.-Forsch., 22, 132 (1972), Hell, et al.: Drugs, 19, 249 (1980),