产品编号：M425478
产品规格：2.5mg
产品价格：面议
| 标准品编号: | M425478 |
| 名称: | ML351 |
| 别名: | 5-(methylamino)-2-(naphthalen-1-yl)-1,3-oxazole-4-carbonitrile; SID 104223766; CID 664510 |
| CAS号: | 847163-28-4 |
| 分子式: | C₁₅H₁₁N₃O |
| 分子量: | 249.27 |
| 种类: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | ML351 is a selective 12/15 LOX inhibitor (IC50 = 200 nM). Exhibits >250-fold selectivity over related isozymes, 5-LOX, platelet 12-LOX, 15-LOX-2, ovine COX-1, and human COX-2. Protects against oxidative glutamate toxicity in mouse neuronal cells (HT-22) and reduces infarct size in a mouse ischemic stroke model. |
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