产品编号：M425090

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M425090
名称:	ML 3403
别名:	4-[5-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-(1-phenylethyl)-2-pyridinamine;
CAS号:	549505-65-9
分子式:	C₂₃H₂₁FN₄S
分子量:	404.5
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ML 3403 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor. MAPK is a key mediator in cytokine-induced signaling events and plays an integral role in disease states including oncogenesis, autoimmune diseases, and inflammatory processes. Therefore, MAPK inhibitors such as ML 3403 provides an attractive strategy for therapeutic intervention.
参考文献	Kammerer, B. et al.: Xenobiotica, 37, 280 (2007); Kammerer, B. et al.: Drug Metab. Dispos., 35, 875 (2007); Gelmedin, V. et al.: Biochem. Pharmacol., 76, 1068 (2008);