产品编号：M325749

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	M325749
名称:	4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-13C6
别名:	4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone-13C6; NNK-13C6 ;
CAS号:	1346600-19-8
参考CAS号:	64091-91-4-unlabelled
分子式:	C₄¹³C₆H₁₃N₃O₂
分子量:	213.19
种类:	Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites; Nicotine Derivatives and Metabolites;
应用:	Labelled NNK (M325750). This compound was present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. It is likely to be important in the etiology of cancers of the lung, oral cavity, and pancreas in people who use tabacco products. Readily produces cancer in rats and hamsters. Carcinogen.
参考文献	Koenigs, L., et al.: Drug Metab. Dispos., 25, 1407 (1997), Gu, J., et al.: Toxicol. Appl. Pharmacol., 165, 158 (2000), Jalas, J., et al.: Chem. Res. Toxicol., 18, 95(2005), Zhu, L., et al.: Drug Metab. Dispos., 34, 1672(2006),