产品编号：M324685

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	M324685
名称:	1-Methyl-4-nitro-5-thioimidazole
别名:	1-Methyl-4-nitro-1H-imidazole-5-thiol; 1-Methyl-4-nitro-imidazole-5-thiol; 5-Mercapto-1-methyl-4-nitroimidazole; Azathioprine BP Impurity D
杂质:	Azathioprine BP Impurity D
CAS号:	6339-54-4
分子式:	C₄H₅N₃O₂S
外观:	Orange to Dark Orange Solid
熔点:	38-42°C
分子量:	159.17
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly, Heated)
稳定性:	Hygroscopic
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-Methyl-4-nitro-5-thioimidazole is a metabolite of Azathioprine (A803350); an immunosuppressive antimetabolite which is also active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects.
参考文献	Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)

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