产品编号：M199250

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	M199250
名称:	MC 1568
别名:	3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;
CAS号:	852475-26-4
分子式:	C₁₇H₁₅FN₂O₃
分子量:	314.31
种类:	Research Tools;
应用:	A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex.
参考文献	Mai, A. et al.: Mol.Pharmacol., 72, 1111 (2007); Mai, A. et al.: J.Med.Chem., 48, 3344 (2005); Nebbioso, A. et al.: Eur. Mol. Biol. Org. Rep., 10, 776 (2009);