产品编号：L486360

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	L486360
名称:	LY 2811376
别名:	(4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-Thiazin-2-amine;
CAS号:	1194044-20-6
分子式:	C₁₅H₁₄F₂N₄S
分子量:	320.36
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.
参考文献	Mikulca, J.. et al: J. Clin. Pharm. Thera., 39, 25 (2014); Lu, Y. et al.: J. Pharm. Exp. Thera., 342, 366 (2012);