产品编号：L329850

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	L329850
名称:	Letaxaban
别名:	1-[1-[(2S)-3-[(6-chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-piperidinyl]tetrahydro-2(1H)-pyrimidinone; TAK 442; 1-[(2S)-3-[(6-Chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(tetrahydro-2-oxo-1(2H)-pyrimidinyl)piperidine; 1-[1-[(2S)-3-[(6-Chloronaphthalen-2-yl)sulfonyl]-2-hydroxypropanoyl]piperidin-4-yl]tetrahydropyrimidin-2(1H)-one;
CAS号:	870262-90-1
分子式:	C₂₂H₂₆ClN₃O₅S
分子量:	479.98
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A potent and selective orally active factor Xa (FXa) inhibitor; anticoagulant. Effective in preventing venous thromboembolism in patient undergoing orthopedic surgery.
参考文献	Zufferey, P.J. et al.: Thromb. Haemost., 104, 1083 (2010); Kawamura, M. et al.: J. Cardio. Pharmacol., 56, 156 (2010); Fujimoto, T. et al.: J. Med. Chem., 53, 3517 (2010);