产品编号：L172475

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	L172475
名称:	Lamivudine (R)-Sulfoxide
别名:	Lamivudine (R)-S-Oxide; 4-Amino-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; 1,3-Oxathiolane, 2(1H)-pyrimidinone Deriv.; [2R-(2α,3β,5α)]-4-Amino-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; GI 138870X; Lamivudine EP Impurity H
杂质:	Lamivudine EP Impurity H
CAS号:	160552-54-5
参考CAS号:	(3S)-isomer: 160552-55-6
分子式:	C₈H₁₁N₃O₄S
外观:	白色固体
熔点:	>230°C (dec.)
分子量:	245.26
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Water (Slightly, heated)
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Lamivudine (R)-Sulfoxide (Lamivudine EP Impurity H) is a metabolite of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.
参考文献	Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977)