产品编号：K660435

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	K660435
名称:	KU-60019
别名:	2-((2R,6S)-2,6-Dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide
CAS号:	925701-46-8
参考CAS号:	Deleted: 925701-49-1, 894104-72-4
分子式:	C₃₀H₃₃N₃O₅S
分子量:	547.67
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	KU-60019 is a potent and reversible inhibitor of ATM kinase, blocking the phosphorylation of ATM substrate proteins. It sensitizes glioma cells to radiation and inhibits migration and invasion of glioma cells in vitro.
参考文献	Golding, S. et al.: Mol. Cancer Ther., 8, 2894 (2009); Golding, S. et al.: Mol. Cancer Ther, 8, 10 (2012);