产品编号：K171000
产品规格：5mg
产品价格：面议
| 标准品编号: | K171000 |
| 名称: | 3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine |
| 别名: | KAAD-Cyclopamine; |
| CAS号: | 306387-90-6 |
| 分子式: | C₄₄H₆₃N₃O₄ |
| 外观: | 白色至Yellow Solid |
| 熔点: | >90°C (dec.) |
| 分子量: | 697.99 |
| 储存: | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| 溶解度: | Chloroform (Slightly), Methanol (Slightly) |
| 种类: | Standards; Steroids; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ß-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity. KAAD-Cyclopamine compound is unstable in solution. |
| 参考文献 | |
