KD 025

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产品编号:K145600

产品规格:25mg

产品价格:面议


产品详情

标准品编号: K145600
名称: KD 025
别名: 2-[3-[4-(1H-Indazol-5-ylamino)-2-quinazolinyl]phenoxy-N-(1-methylethyl)-acetamide;
CAS号: 911417-87-3
分子式: C₂₆H₂₄N₆O₂
外观: 白色至淡黄色固体
熔点: >228ºC (dec.)
分子量: 452.51
储存: -20°C Freezer
溶解度: Methanol (Slightly)
种类: Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用: KD 025 is an inhibitor of Rho-associated protein kinase II (ROCK-II), a serine/threonine kinase that regulates the formation of actin stress fibers and focal adhesions, smooth muscle contraction, and gene expression (1, 2). KD025 has been shown to reduce infarct volume after transient middle cerebral artery occlusion (2).
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