产品编号:K145600
产品规格:25mg
产品价格:面议
| 标准品编号: | K145600 |
| 名称: | KD 025 |
| 别名: | 2-[3-[4-(1H-Indazol-5-ylamino)-2-quinazolinyl]phenoxy-N-(1-methylethyl)-acetamide; |
| CAS号: | 911417-87-3 |
| 分子式: | C₂₆H₂₄N₆O₂ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | >228ºC (dec.) |
| 分子量: | 452.51 |
| 储存: | -20°C Freezer |
| 溶解度: | Methanol (Slightly) |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | KD 025 is an inhibitor of Rho-associated protein kinase II (ROCK-II), a serine/threonine kinase that regulates the formation of actin stress fibers and focal adhesions, smooth muscle contraction, and gene expression (1, 2). KD025 has been shown to reduce infarct volume after transient middle cerebral artery occlusion (2). |
| 参考文献 | |