产品编号：K000450
产品规格：25mg
产品价格：面议
| 标准品编号: | K000450 |
| 名称: | K 114 |
| 别名: | 4,4'-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis[phenol] |
| CAS号: | 872201-12-2 |
| 分子式: | C₂₂H₁₇BrO₂ |
| 分子量: | 393.27 |
| 种类: | Research Tools; Molecular Biology; Fluorescent Reagents; Dyes; |
| 应用: | K 114 is a potent amyloid fibril-specific fluorescent dye. K 114 is a potent amyloid fibril-specific fluorescent dye similar to Congo Red and BSB. K 114 recognizes amyloid lesions and facilitates quantitative monitoring of the formation of amyloid fibrils assembled from the Aβ peptide, α-synuclein, and tau. The affinity for fibrils ranges 20-30 nM. Unlike the other compounds K114 has minimal fluorescence in aqueous buffers, but fluoresces brightly in the presence of amyloid fibrils. K114 can be used to monitor in vitro amyloid fibril formation by fluorescence emission at 550 nm. |
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