产品编号：I728900

产品规格：25 g

产品价格：面议

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产品详情

标准品编号:	I728900
名称:	5-Iodouracil
别名:	5-Iodo-2,4(1H,3H)-pyrimidinedione; 5-Iodo-2,4-dihydroxypyrimidine; 5-Iodo-2,4-pyrimidinedione; 5-Iodopyrimidine-2,4-diol; 5-Iodouracil; NSC 57848;
CAS号:	696-07-1
分子式:	C₄H₃IN₂O₂
外观:	白色至白色固体
熔点:	>250ºC (dec.)
分子量:	237.98
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
种类:	Research Tools; Molecular Biology; Cross-linkers;
应用:	5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.
参考文献	Meisenheimer, K. et al.: Meth. Enzymol., 318, 88 (2000); Klecker, R.W. Jr. et al.: Cancer Chemother. Pharmacol., 48, 407 (2001); Turner, D.P. et al.: Cancer Res., 66, 7686 (2006);