产品编号:I527500
产品规格:2mg
产品价格:面议
| 标准品编号: | I527500 |
| 名称: | Indirubin-3’-monoxime |
| 别名: | Indirubin-3’-oxime; 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one; |
| CAS号: | 160807-49-8 |
| 分子式: | C₁₆H₁₁N₃O₂ |
| 外观: | Dark Red Solid |
| 熔点: | 247-249°C (dec.) |
| 分子量: | 277.28 |
| 储存: | -20°C Freezer |
| 溶解度: | DMSO, Methanol |
| 稳定性: | Light Sensitive |
| 种类: | Standards; Enzyme Activators and Inhibitors; |
| 应用: | A potent inhibitor of GSK-3ß (IC50=22nM). Also inhibits CDK1 (IC50=180nM) and CDK (IC50=100nM). It reversibly arrests asynchronous HBL-100 cells at G2. It induces apoptosis in the mammary carcinoma cell line MCF-7 (10üM). |
| 参考文献 | |