Indirubin-3’-monoxime

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产品编号:I527500

产品规格:2mg

产品价格:面议


产品详情

标准品编号: I527500
名称: Indirubin-3’-monoxime
别名: Indirubin-3’-oxime; 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one;
CAS号: 160807-49-8
分子式: C₁₆H₁₁N₃O₂
外观: Dark Red Solid
熔点: 247-249°C (dec.)
分子量: 277.28
储存: -20°C Freezer
溶解度: DMSO, Methanol
稳定性: Light Sensitive
种类: Standards; Enzyme Activators and Inhibitors;
应用: A potent inhibitor of GSK-3ß (IC50=22nM). Also inhibits CDK1 (IC50=180nM) and CDK (IC50=100nM). It reversibly arrests asynchronous HBL-100 cells at G2. It induces apoptosis in the mammary carcinoma cell line MCF-7 (10üM).
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