产品编号：H950180

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	H950180
名称:	4-Hydroxy-PAC 1-β-D-Glucopyranosiduronic Acid
别名:	(2S,3S,4S,5R,6S)-6-(2-Allyl-4-((E)-(2-(2-(4-benzylpiperazin-1-yl)acetyl)hydrazono)methyl)-3-hydroxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid
分子式:	C₂₉H₃₆N₄O₉
分子量:	584.62
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用:	4-Hydroxy-PAC 1-β-D-Glucopyranosiduronic Acid is a metabolite of PAC-1 (P132000),which is a potential anti-tumor drug candidate that activates caspase 3 and induces apoptosis in both in vitro and in vivo against mice tumors. Metabolites andderivatives of PAC-1 are useful compounds to investigate the mechanism of action and toserve as standards(ie. LC/MS).
参考文献	Ren, L., et al.:J. Chromatogr. B (2008);Slee, E., et al.: J. Biol. Chem., 276, 7320 (2001); Pop, C., et al.: Biochemistry, 42, 12311 (2003); Li, L., et al.: Science, 305, 1471 (2004); Green, D., et al.: J. Clin. Invest., 115, 2610 (2005); Satoh, T., et al.: Clin. Cancer Res., 15, 3872 (2009)