产品编号：H946805

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	H946805
名称:	2-Hydroxy-2-(6'-(hydroxymethyl)-5'-oxo-3',5',8',8a'-tetrahydro-2'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)-N-((S)-1-phenylethyl)propanamide
分子式:	C₂₂H₂₈N₂O₆
外观:	白色固体
分子量:	416.47
溶解度:	Chloroform, DCM, Ethyl Acetate, Ether,Toluene
种类:	Building Blocks; Chiral Molecules;
应用:	2-Hydroxy-2-(6'-(hydroxymethyl)-5'-oxo-3',5',8',8a'-tetrahydro-2'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)-N-((S)-1-phenylethyl)propanamide is an intermediate in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor and also a derivative of Camptothecin (C175145), an antitumor alkaloid.
参考文献	Fan, Y., et al.: J. Med. Chem., 41, 2216 (1998), Kaufmann, S.H., et al.: Biochim. Biophys. Acta, 1400, 195 (1998),