产品编号：H825605

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	H825605
名称:	(19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin
别名:	(2S)-1-[2-Oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19E,21R)-14-hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen-1-yl]-3-methyl-2H-pyran-2-yl]acetyl]-2-piperidinecarboxylic Acid
杂质:	Everolimus EP Impurity B Isomer
CAS号:	1062122-63-7
分子式:	C₅₃H₈₃NO₁₄
外观:	Yellow Solid
分子量:	958.22
溶解度:	Dichloromethane, Methanol
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(19E/Z)-seco-[4-O-(2-Hydroxyethyl)] Rapamycin is a metabolite of the immunosuppressant macrolide SDZ RAD (also known as Everolimus E945400) which is an analog of the parent drug Rapamycin (R124000).
参考文献	Vidal, C. et al.: J. Am. Soc. Mass Spec., 9, 1267 (1998); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001);