产品编号：H825287

产品规格：

产品价格：面议

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产品详情

标准品编号:	H825287
名称:	12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid-d4
别名:	[S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-HETE-d4; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-Hydroxyeicosatetraenoic Acid-d4; 12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4;
参考CAS号:	Unlabelled: 54397-83-0
分子式:	C₂₀H₂₈D₄O₃
分子量:	324.49
种类:	Standards; Isotopic Labeled Analogues; Lipids/Fatty Acids, Glycerol Derivatives;
应用:	A labelled fatty acid metabolite of arachidonic acid (A765000). Potential biomarker for asthma monitoring and diagnosis. Stimulates protein kinase C-mediated release of cathepsin B from malignant cells. Used in the study of mechanisms controlling cell cycle arrest and induction of apoptosis in prostate cancer cells via 12-lipoxygenase inhibition.
参考文献	Nording, M.L. et al.: IEEE Sensors J., 10, 123 (2010); Pidgeon, G.P. et al.: Canc. Res., 62, 2721 (2002); Honn, K.V. et al.: Exp. Cell Res., 214, 120 (1994); Feldstein, A.E. et al.: J. Lipid Res., 51, 3046 (2010);