产品编号：G931500
产品规格：5mg
产品价格：面议
| 标准品编号: | G931500 |
| 名称: | GW 501516 |
| 别名: | 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid; Methyl-methyl-trifluoromethylphenyl -thiazolyl-methylsulfanyl-phenoxy-acetic Acid; GW 1516; Endurobol |
| CAS号: | 317318-70-0 |
| 参考CAS号: | 813458-54-7 |
| 分子式: | C₂₁H₁₈F₃NO₃S₂ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | 134 - 144°C |
| 分子量: | 453.5 |
| 储存: | 冰箱 |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 稳定性: | No Data available |
| 种类: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells. GW 501516 has been found to enhance endurance in mice without any training. |
| 参考文献 | |
