产品编号：G797725

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	G797725
名称:	GSK 690693 Hydrochloride
别名:	4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-Butyn-2-ol;
CAS号:	1029067-05-7
参考CAS号:	Free Base: 937174-76-0
分子式:	C₂₁H₂₈ClN₇O₃
外观:	淡黄色固体
熔点:	>178ºC (dec.)
分子量:	461.95
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly)
种类:	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	GSK 690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. Also plays a role in the inhibition of other members of the AGC family of kinases which prevents the phosphorylation of downstream Akt substrates resulting in the induction of apoptosis in human tumor cells. Anti-proliferative agent.
危险品:	Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献	Rhodes, N. et al.: Canc. Res., 68, 2366 (2008);