产品编号：H296910

产品规格：500mg

产品价格：面议

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产品详情

标准品编号:	H296910
名称:	2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-Thiazolecarboxylic Acid Ethyl Ester
CAS号:	1271738-74-9
分子式:	C₁₈H₂₂N₂O₄S
外观:	Yellow Solid
分子量:	362.44
溶解度:	Dichloromethane; Ethyl Acetate
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-[3-[(Hydroxyimino)methyl]-4-(2-methylpropoxy)phenyl]-4-methyl-5-Thiazolecarboxylic Acid Ethyl Ester, is an impurity of Febuxostat (F229000), an Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
参考文献	Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),