产品编号：F598450

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	F598450
名称:	(4R)-3-[(2R,5S)-5-(2-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
分子式:	C₃₉H₄₆F₂N₂O₅Si₂
分子量:	716.96
溶解度:	DCM, Ethyl Acetate
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(4R)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone is an intermediate in the synthesis of 3’-(2-Fluorophenyl) Ezetimibe (F595370). 3’-(2-Fluorophenyl) Ezetimibe is an impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and a cholesterol absorption inhibitor.
参考文献	van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)